Recombination Frequency Calculator:
Enter the values of recombinant offspring, RCO and total offspring, TO to determine the value of Recombination frequency, RF.
Recombination Frequency Formula:
Recombination frequency (RF) is a measure of the genetic distance between two loci on a chromosome, indicating how often a crossover event occurs between them during meiosis. It is expressed as a percentage and represents the likelihood that recombination will separate alleles at the two loci. This concept is central to genetic mapping and is used to determine the relative positions of genes on a chromosome.
RF is calculated as the ratio of the number of recombinant offspring (RCO) to the total offspring (TO), multiplied by 100 to express it as a percentage. Recombinant offspring arise due to crossing-over, which exchanges genetic material between homologous chromosomes. RF values range from 0% (no recombination) to 50% (independent assortment), with higher RF indicating greater genetic distance.
Recombination frequency is a critical tool in understanding inheritance patterns and mapping genes, particularly in determining the sequence and physical distances between genetic markers. RF below 50% implies linkage, where loci are on the same chromosome and inherited together more often than expected by chance. Conversely, an RF of 50% or above suggests loci are unlinked.
Recombination frequency, RF in percentage equals the ratio of recombinant offspring, RCO to the total offspring, TO, multiplied by 100.
Recombination frequency, RF = RCO / TO * 100
RF = recombination frequency in percentage.
RCO = recombinant offspring.
TO = total offspring.
Recombination Frequency Calculation:
- A genetic experiment resulted in 30 recombinant offspring and a total of 200 offspring. Calculate the recombination frequency.
Given: RCO = 30, TO = 200.
Recombination frequency, RF = RCO / TO * 100
RF = 30 / 200 * 100
RF = 15%.
- In another experiment, the recombination frequency was found to be 20%, and the total offspring were 500. Calculate the number of recombinant offspring.
Given: RF = 20%, TO = 500.
Recombination frequency, RF = RCO / TO * 100
RCO = RF * TO / 100
RCO = 20 * 500 / 100
RCO = 100.